# ACACIA SENEGAL GUM (acacia-senegal-gum) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/acacia-senegal-gum
- **Standard INCI**: `ACACIA SENEGAL GUM`
- **KR MFDS Standard Name**: `아라비아고무나무검`
- **CAS No.**: `9000-01-5`
- **EC / EINECS No.**: `232-519-5`
- **Origin**: `plant`
- **Functions**: 필름형성제, 향료
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 아라비아고무나무검 |
| KR (Former Names) | 아라비아고무 |
| EU (CosIng 1223/2009) | ACACIA SENEGAL GUM |
| US (PCPC / MoCRA INCI) | ACACIA SENEGAL GUM |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | 阿拉伯胶树(ACACIA SENEGAL)胶 |
| JP (JCIA / MHLW QD) | ACACIA SENEGAL GUM  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `1017`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- Listed within general cosmetic GMP safety thresholds.

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: ACACIA SENEGAL GUM | CAS No.: 9000-01-5 | EC No.: 232-519-5
  - Origin: PLANT | Functions: , 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [ACACIA SENEGAL GUM] · EU [ACACIA SENEGAL GUM] · CN [阿拉伯胶树(ACACIA SENEGAL)胶] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - Acacia Senegal Gum is the dried, gummy exudate of the acacia, Acacia senegal, Leguminosae Classified under origin 'plant', it acts within the cosmetic vehicle or stratum corneum to deliver ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 1017 (阿拉伯胶树(ACACIA SENEGAL)胶))
  - No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment).
  - Official Safety & Historical Use Concentration (Layer 2): Quantum satis (QS) within standard cosmetic safety margins
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [emulsion_cream] Typical range: 0.1 ~ 1.0% (Median 0.25%, Ref: Global Starter Formulation Library Statistical Distribution (n=10, SEPPIC 10)) — Emulsion cream & lotion structural / conditioning agent
  - [sun_color] Typical range: 0.2 ~ 1.0% (Median 0.5%, Ref: Global Starter Formulation Library Statistical Distribution (n=5, SEPPIC 3 · EVONIK 2)) — Sun care & color cosmetics dispersion / sensory modifier
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase or Cool-down Phase (< 45°C)
  - Optimal pH Range: pH 4.0 ~ 8.0 | Max Process Temp: Max 50°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Verify phase compatibility under extreme pH or high electrolyte loads
  - Synergy Pairings: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL | Reference Trade Names: ACACIA SENEGAL GUM
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - PMID 16422266 (2005, Int J Toxicol): Final report of the safety assessment of Acacia catechu gum, Acacia concinna fruit extract, Acacia dealbata leaf extract
  - PMID 39643419 (2025, Carbohydr Polym): Structural analysis of gum arabic side chains from Acacia seyal released by bifidobacterial β-arabino-oligosaccharide 3-
  - PMID 39168198 (2024, Int J Biol Macromol): Facile synthesis and optimization of Acacia senegal gum hydrogel for kinetically treated adsorptive removal of targeted 

## 6. Linked PubMed Literature
- [PMID: 16422266] Final report of the safety assessment of Acacia catechu gum, Acacia concinna fruit extract, Acacia dealbata leaf extract, Acacia dealbata leaf wax, Acacia decurrens extract, Acacia farnesiana extract, Acacia farnesiana flower wax, Acacia farnesiana gum, Acacia senegal extract, Acacia senegal gum, and Acacia senegal gum extract — *Int J Toxicol* (2005)
- [PMID: 39643419] Structural analysis of gum arabic side chains from Acacia seyal released by bifidobacterial β-arabino-oligosaccharide 3-O-β-l-arabinopyranosyl-α-l-arabinofuranosidase — *Carbohydr Polym* (2025)
- [PMID: 39168198] Facile synthesis and optimization of Acacia senegal gum hydrogel for kinetically treated adsorptive removal of targeted industrial effluents — *Int J Biol Macromol* (2024)
- [PMID: 34645930] Acacia senegal gum attenuates systemic toxicity in CCl(4)-intoxicated rats via regulation of the ROS/NF-κB signaling pathway — *Sci Rep* (2021)
- [PMID: 33540787] The Ameliorative Role of Acacia senegal Gum against the Oxidative Stress and Genotoxicity Induced by the Radiographic Contrast Medium (Ioxitalamate) in Albino Rats — *Antioxidants (Basel)* (2021)
- [PMID: 32891160] Potential Role of Acacia Senegal (Gum Arabic) as Immunomodulatory Agent among newly diagnosed COVID 19 Patients: A structured summary of a protocol for a randomised, controlled, clinical trial — *Trials* (2020)
- [PMID: 32487516] A gum Arabic assisted sustainable drug delivery system for adult Drosophila — *Biol Open* (2020)
- [PMID: 31931422] Improvement of the foamability of sparkling base wines by the addition of Acacia gums — *Food Chem* (2020)
- [PMID: 31905015] Anti-ulcerogenic activity of Gum Arabic in gastric mucosal injury induced by ethanol in male albino rats — *Appl Physiol Nutr Metab* (2020)
- [PMID: 31316836] Acacia Senegal (Gum Arabic) Supplementation Modulate Lipid Profile and Ameliorated Dyslipidemia among Sickle Cell Anemia Patients — *J Lipids* (2019)
- [PMID: 37385018] Nephroprotective effects of Acacia senegal against aflatoxicosis via targeting inflammatory and apoptotic signaling pathways — *Ecotoxicol Environ Saf* (2023)