# BEHENTRIMONIUM CHLORIDE (behentrimonium-chloride) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/behentrimonium-chloride
- **Standard INCI**: `BEHENTRIMONIUM CHLORIDE`
- **KR MFDS Standard Name**: `베헨트라이모늄클로라이드`
- **CAS No.**: `17301-53-0`
- **EC / EINECS No.**: `241-327-0`
- **Origin**: `synthetic`
- **Functions**: 대전방지제, 모발컨디셔닝제, 방부제
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 베헨트라이모늄클로라이드 |
| KR (Former Names) | 베헨트리모늄클로라이드 |
| EU (CosIng 1223/2009) | BEHENTRIMONIUM CHLORIDE |
| US (PCPC / MoCRA INCI) | BEHENTRIMONIUM CHLORIDE |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | 山嵛基三甲基氯化铵 |
| JP (JCIA / MHLW QD) | BEHENTRIMONIUM CHLORIDE  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `restricted`
- **EU (1223/2009)**: `restricted`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `5956`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- **reported_use** (hair): 0.2~7% — 115_draft_trimon.pdf (null)
- **reported_use** (spray): 0.2~1% — 115_draft_trimon.pdf (null)
- **reported_use** (rinse_off): 3~3% — 115_draft_trimon.pdf (null)
- **reported_use** (hair_dye): 2~3% — 115_draft_trimon.pdf (null)
- **reported_use** (dermal): 0.5~0.9% — 115_draft_trimon.pdf (null)
- **sccs_opinion** (rinse_off): ≤ 5% — undefined (undefined)
- **sccs_opinion** (leave_on): ≤ 3% — undefined (undefined)

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: BEHENTRIMONIUM CHLORIDE | CAS No.: 17301-53-0 | EC No.: 241-327-0
  - Origin: SYNTHETIC | Functions: , , 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [BEHENTRIMONIUM CHLORIDE] · EU [BEHENTRIMONIUM CHLORIDE] · CN [山嵛基三甲基氯化铵] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - Behentrimonium Chloride is the quaternary ammonium salt that conforms to the formula: Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver , ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: RESTRICTED | EU: RESTRICTED | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 5956 (山嵛基三甲基氯化铵))
  - [EU / COMPOSITION / limited] (Max 5%): 
  - [EU / COMPOSITION / limited] (Max 0.1%): 
  - [KR / COMPOSITION / limited] (Max 5%): 
  - Official Safety & Historical Use Concentration (Layer 2): cir (reported_use, hair): 0.2~7% / cir (reported_use, spray): 0.2~1% / cir (reported_use, rinse_off): 3~3%
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [cleanser_rinse] Typical range: 0.5 ~ 3.0% (Median 2.175%, Ref: Global Starter Formulation Library Statistical Distribution (n=16, EVONIK 11 · GRANT 4 · SEPPIC 1)) — Rinse-off cleanser & surfactant system modifier
  - [emulsion_cream] Typical range: 0.5 ~ 3.0% (Median 1.475%, Ref: Global Starter Formulation Library Statistical Distribution (n=10, GRANT 10)) — Emulsion cream & lotion structural / conditioning agent
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase or Cool-down Phase (< 45°C)
  - Optimal pH Range: pH 4.0 ~ 8.0 | Max Process Temp: Max 50°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Verify phase compatibility under extreme pH or high electrolyte loads
  - Synergy Pairings: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL | Reference Trade Names: BEHENTRIMONIUM CHLORIDE
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - PMID 41126531 (2026, Int J Cosmet Sci): Electrokinetic analysis reveals common conditioner ingredient interactions with human hair
  - PMID 33811764 (2021, Int J Cosmet Sci): Investigation of the interactions of cationic guar with human hair by electrokinetic analysis
  - PMID 24064305 (2013, Toxicol In Vitro): Confirmation of in vitro and clinical safety assessment of behentrimonium chloride-containing leave-on body lotions usin

## 6. Linked PubMed Literature
- [PMID: 41126531] Electrokinetic analysis reveals common conditioner ingredient interactions with human hair — *Int J Cosmet Sci* (2026)
- [PMID: 33811764] Investigation of the interactions of cationic guar with human hair by electrokinetic analysis — *Int J Cosmet Sci* (2021)
- [PMID: 24064305] Confirmation of in vitro and clinical safety assessment of behentrimonium chloride-containing leave-on body lotions using post-marketing adverse event data. — *Toxicol In Vitro* (2013)
- [PMID: 30854438] Repeatability of Quantitative Diffusion-Weighted Imaging Metrics in Phantoms, Head-and-Neck and Thyroid Cancers: Preliminary Findings — *Tomography* (2019)