# CHOLESTEROL (cholesterol) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/cholesterol
- **Standard INCI**: `CHOLESTEROL`
- **KR MFDS Standard Name**: `콜레스테롤`
- **CAS No.**: `57-88-5`
- **EC / EINECS No.**: `200-353-2`
- **Origin**: `synthetic`
- **Functions**: 피부컨디셔닝제, 점도조절제, 에모리엔트, 유화제, 광안정제
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 콜레스테롤 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | CHOLESTEROL |
| US (PCPC / MoCRA INCI) | CHOLESTEROL |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | 胆甾醇 |
| JP (JCIA / MHLW QD) | コレステロール (QD: コレステロール) |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `1819`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- **cn_iecic_max** (leave_on): ≤ 5% — NMPA IECIC (2025) Entry 01875 (2025)
- **cn_iecic_max** (rinse_off): ≤ 3% — NMPA IECIC (2025) Entry 01875 (2025)

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4.5 – 7.5
- **Max Process Temp**: ≤ 70°C
- **Synergy Pairings**: —
- **Incompatibilities**: —

## 5. Academic Monograph


## 6. Linked PubMed Literature
- [PMID: 42288877] Remnant cholesterol inflammation index may be a superior biomarker to C-reactive protein-triglyceride glucose index in predicting carotid atherosclerosis risk — *BMC Endocr Disord* (2026)
- [PMID: 42315554] Associations of genetic and non-genetic cardiovascular health metrics with coronary artery disease incidence in cancer survivors — *Sci Rep* (2026)
- [PMID: 42311419] Topical Statins in Porokeratosis: Case Report with Focused Literature Review — *Case Rep Dermatol* (2026)
- [PMID: 42306542] Lipid nanoparticle formulations including stereochemically defined glycomacromolecules for delivery of saRNA — *Chem Sci* (2026)
- [PMID: 42301958] GnRH Analog followed by Sex Hormone Therapy as a Preventive Strategy against Ovarian Complications in Congenital Lipoid Adrenal Hyperplasia: A Case Report — *Horm Res Paediatr* (2026)
- [PMID: 42291515] Comparative analysis of physiological, biochemical and immunological responses to heat stress in hybrid and purebred ducks in tropical environments — *Vet Anim Sci* (2026)
- [PMID: 42280233] 1,8-Cineole Alleviates PA-Induced Lipid Accumulation, Oxidative Stress, and Inflammation via the TLR4/MyD88/NF-κB Signaling Pathway — *Molecules* (2026)
- [PMID: 42276549] Extracellular wax ester biosynthesis by staphylococcal lipases detoxifies skin fatty acids and shapes interspecies competition — *ISME J* (2026)
- [PMID: 42255990] Eruptive xanthomas: a case report with literature review focusing on pathogenesis and clinical management — *Open Life Sci* (2026)
- [PMID: 42250632] The impact of avobenzone and oxybenzone on fibroblast and keratinocyte membranes. Searching for the role of lipids in the effect of UV filters on skin cells — *Chem Phys Lipids* (2026)
- [PMID: 42246839] Routine blood monitoring in acne vulgaris patients on isotretinoin: Is reassessment warranted? A retrospective cohort study from Tygerberg Hospital — *S Afr Med J* (2026)
- [PMID: 42243873] An explainable machine learning method for identifying key atherogenic lipid biomarkers in abdominal obesity among the Southern Chinese population — *Lipids Health Dis* (2026)