# DISODIUM EDTA (disodium-edta) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/disodium-edta
- **Standard INCI**: `DISODIUM EDTA`
- **KR MFDS Standard Name**: `다이소듐이디티에이`
- **CAS No.**: `139-33-3`
- **EC / EINECS No.**: `205-358-3`
- **Origin**: `synthetic`
- **Functions**: 킬레이트제, 점도조절제
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 다이소듐이디티에이 |
| KR (Former Names) | 디소듐이디티에이 |
| EU (CosIng 1223/2009) | DISODIUM EDTA |
| US (PCPC / MoCRA INCI) | DISODIUM EDTA |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | EDTA 二钠 |
| JP (JCIA / MHLW QD) | ＥＤＴＡ－２Ｎａ (QD: エデト酸二ナトリウム) |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `388`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- **cn_iecic_max** (leave_on): ≤ 0.5% — NMPA IECIC (2025) Entry 00215 (2025)
- **cn_iecic_max** (rinse_off): ≤ 0.5% — NMPA IECIC (2025) Entry 00215 (2025)

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph


## 6. Linked PubMed Literature