# SCLEROTIUM GUM (sclerotium-gum) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/sclerotium-gum
- **Standard INCI**: `SCLEROTIUM GUM`
- **KR MFDS Standard Name**: `스클레로튬검`
- **CAS No.**: `39464-87-4`
- **EC / EINECS No.**: `254-464-6`
- **Origin**: `plant`
- **Functions**: 피부컨디셔닝제, 점도조절제, 유화안정제
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 스클레로튬검 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | SCLEROTIUM GUM |
| US (PCPC / MoCRA INCI) | SCLEROTIUM GUM |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | 小核菌(SCLEROTIUM ROLFSSII)胶 |
| JP (JCIA / MHLW QD) | SCLEROTIUM GUM  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `7096`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- **cn_iecic_max** (leave_on): ≤ 2% — NMPA IECIC (2025) Entry 07592 (2025)
- **cn_iecic_max** (rinse_off): ≤ 1.5% — NMPA IECIC (2025) Entry 07592 (2025)

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 3 – 10
- **Max Process Temp**: ≤ 85°C
- **Synergy Pairings**: XANTHAN GUM, ACACIA SENEGAL GUM, GLYCERIN
- **Incompatibilities**: Requires heating to 70~80°C for complete hydration and maximum clarity

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: SCLEROTIUM GUM | CAS No.: 39464-87-4 | EC No.: 254-464-6
  - Origin: PLANT | Functions: Skin Conditioning, , 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [SCLEROTIUM GUM] · EU [SCLEROTIUM GUM] · CN [小核菌(SCLEROTIUM ROLFSSII)胶] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - Sclerotium rolfssii gum Classified under origin 'plant', it acts within the cosmetic vehicle or stratum corneum to deliver , ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 7096 (小核菌(SCLEROTIUM ROLFSSII)胶))
  - No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment).
  - Official Safety & Historical Use Concentration (Layer 2): CN_IECIC_2025 (cn_iecic_max, leave_on): Max 2.0% / CN_IECIC_2025 (cn_iecic_max, rinse_off): Max 1.5%
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [aqueous_serum] Typical range: 0.1 ~ 1.5% (Median 0.45%, Ref: Alban Muller Amigel / SEPPIC SOLAGUM AX TDS) — Clean-beauty non-stringy silky hydrogel builder
  - [emulsion_cream] Typical range: 0.1 ~ 1.0% (Median 0.3%, Ref: CIR Sclerotium Gum Safety Assessment) — Natural emulsion thermal & suspension stabilizer
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase (Heat to 70~80°C with homogenization for full hydration)
  - Optimal pH Range: pH 3.0 ~ 10.0 | Max Process Temp: Max 85°C | Electrolyte Tolerance: HIGH
  - Incompatibility / Caution: Requires heating to 70~80°C for complete hydration and maximum clarity
  - Synergy Pairings: XANTHAN GUM, ACACIA SENEGAL GUM, GLYCERIN | Reference Trade Names: Amigel®, SOLAGUM™ AX, Actigum™ CS 11
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - Validated against official regulatory compendia (MFDS/CosIng/CIR/SCCS) and physicochemical standards.

## 6. Linked PubMed Literature