# SODIUM STEAROYL GLUTAMATE (sodium-stearoyl-glutamate) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/sodium-stearoyl-glutamate
- **Standard INCI**: `SODIUM STEAROYL GLUTAMATE`
- **KR MFDS Standard Name**: `소듐스테아로일글루타메이트`
- **CAS No.**: `38517-23-6`
- **EC / EINECS No.**: `253-980-9`
- **Origin**: `synthetic`
- **Functions**: 세정제, 모발컨디셔닝제, 피부컨디셔닝제, 유화제
- **Molecular Formula / MW**: `C23H42NNaO5` (433.56 g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 소듐스테아로일글루타메이트 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | SODIUM STEAROYL GLUTAMATE |
| US (PCPC / MoCRA INCI) | SODIUM STEAROYL GLUTAMATE |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | 硬脂酰谷氨酸钠 |
| JP (JCIA / MHLW QD) | SODIUM STEAROYL GLUTAMATE  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `8058`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- Listed within general cosmetic GMP safety thresholds.

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 5 – 8
- **Max Process Temp**: ≤ 85°C
- **Synergy Pairings**: POLYGLYCERYL-3 METHYLGLUCOSE DISTEARATE, CETEARYL ALCOHOL, GLYCERYL STEARATE
- **Incompatibilities**: Co-emulsifying charge repulsion diminishes below pH 4.5 due to protonation of carboxylate groups

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: SODIUM STEAROYL GLUTAMATE | CAS No.: 38517-23-6 | EC No.: 253-980-9
  - Origin: SYNTHETIC | Functions: , , , 
  - Physicochemical Profile: Formula C23H42NNaO5 | MW 433.56 g/mol | /   | Ionic Nature: anionic | PubChem CID 23672308
  - Official Regional Label Names: US [SODIUM STEAROYL GLUTAMATE] · EU [SODIUM STEAROYL GLUTAMATE] · CN [硬脂酰谷氨酸钠] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - SODIUM STEAROYL GLUTAMATE functions primarily as , , ,  in dermatological and cosmetic formulations. Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver , , ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 8058 (硬脂酰谷氨酸钠))
  - No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment).
  - Official Safety & Historical Use Concentration (Layer 2): Quantum satis (QS) within standard cosmetic safety margins
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [emulsion_cream] Typical range: 0.1 ~ 1.5% (Median 0.35%, Ref: BASF Eumulgin SG / Evonik TEGO Care PSC 3 TDS & CIR) — Anionic amino-acid co-emulsifier enhancing droplet zeta-potential
  - [sun_color] Typical range: 0.2 ~ 1.5% (Median 0.5%, Ref: CIR Amino Acid Alkyl Amides Assessment) — Sunscreen thermal stability booster
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water or Oil Phase (75~80°C)
  - Optimal pH Range: pH 5.0 ~ 8.0 | Max Process Temp: Max 85°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Co-emulsifying charge repulsion diminishes below pH 4.5 due to protonation of carboxylate groups
  - Synergy Pairings: POLYGLYCERYL-3 METHYLGLUCOSE DISTEARATE, CETEARYL ALCOHOL, GLYCERYL STEARATE | Reference Trade Names: Eumulgin® SG, Amisoft® HS-11P
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - Validated against official regulatory compendia (MFDS/CosIng/CIR/SCCS) and physicochemical standards.

## 6. Linked PubMed Literature