What are the official 7-track regulatory label names for COCO-GLUCOSIDE?

Standard label names are US PCPC INCI: 'COCO-GLUCOSIDE', EU CosIng: 'COCO-GLUCOSIDE', KR MFDS: 'COCO-GLUCOSIDE (KR MFDS Registered)', CN NMPA IECIC: '椰油基葡糖苷', and JP JCIA: 'COCO-GLUCOSIDE'.

Is COCO-GLUCOSIDE restricted or permitted in EU, US, KR, CN, and JP cosmetics?

Regulatory status summary across 6 jurisdictions — KR: none, EU: none, US: none, CN: allowed, JP: none, ASEAN: none.

What is the typical formulation concentration and optimal pH window for COCO-GLUCOSIDE?

In cleanser_rinse systems, COCO-GLUCOSIDE is typically formulated between 1.5% and 20% (median 6%), with an optimal stability window of pH 4.5–9.

What are the known formulation incompatibilities and synergy pairings for COCO-GLUCOSIDE?

Recommended synergy pairings include SODIUM COCOYL ISETHIONATE, COCAMIDOPROPYL BETAINE, GLYCERYL OLEATE, CITRIC ACID. Key incompatibilities to avoid: Supplied at alkaline pH (11.5~12.0); must adjust final formulation pH to 5.0~6.0 using Citric Acid.

Synthetic

COCO-GLUCOSIDE

CleansingFoaming

[EU CosIng Official Definition] Coco-Glucoside is the product obtained by the condensation of coconut alcohol with glucose.

Executive Regulatory & Safety Fact BoxAEO / GEO CITATION ANCHOR

What is COCO-GLUCOSIDE (CAS 110615-47-9) in cosmetics and what are its global regulatory limits?

COCO-GLUCOSIDE (CAS No. 110615-47-9) is a verified cosmetic ingredient primarily functioning as Cleansing, Foaming in topical formulations. Regulated under KR MFDS (Unregulated) and EU 1223/2009 CosIng (Unregulated) statutory frameworks, it is typically formulated at 1.5–20% within an optimal stability window of pH 4.5–9.

7-Track Official Regulatory Label Names Matrix

Primary Statutory Gazette Only · Zero Machine Translation

7-Track Official Statutory Label Names for COCO-GLUCOSIDE
Jurisdiction Track	Official Statutory Label Name	One-Click Copy
1. Korea (MFDS Standard Name)	COCO-GLUCOSIDE (KR MFDS Registered)
2. Korea Former Nomenclature History	—	—
3. European Union (EU CosIng Glossary)	COCO-GLUCOSIDE
4. United States (US PCPC / MoCRA INCI)	COCO-GLUCOSIDE
5. US FDA OTC Monograph Active Name	— (Cosmetic Inactive / Non-OTC)	—
6. China (NMPA IECIC Standard Name)	椰油基葡糖苷
7. Japan (JCIA Standard / MHLW Quasi-Drug)	COCO-GLUCOSIDE (Standard INCI Reference)

Layer 1 — Statutory Regulatory Limits Across 6 Regions

Layer 1 Statutory Regulatory Limits Across 6 Regions for COCO-GLUCOSIDE
Region	Status	Max Limit	Conditions & Statutory Source
Korea (MFDS)	Unregulated	GMP	Listed in official cosmetic inventory
Europe (EU)	Unregulated	GMP	Listed in official cosmetic inventory
United States (FDA)	Unregulated	GMP	Listed in official cosmetic inventory
China (NMPA)	Listed / Allowed	GMP	IECIC Entry #7519
Japan (MHLW)	Unregulated	GMP	Listed in official cosmetic inventory
ASEAN (ACD)	Unregulated	GMP	Listed in official cosmetic inventory

Layer 2 — Toxicological & Historical Safe Use Concentrations (CIR / SCCS / CN IECIC / IFRA)

“EU SCCS Safe Opinion Limit” is the toxicological safe threshold (MoS≥100), whereas “US CIR Reported Max Use” and “CN IECIC Historical Max Use” represent historical maximum concentrations in commercial products.

Layer 2 Toxicological & Historical Safe Use Concentrations for COCO-GLUCOSIDE
Assessment Basis	Application Scope	Concentration Range	Verdict & Dossier Reference
CN IECIC Historical Max Use	leave_on	≤ 5%	Safe (MoS≥100)NMPA IECIC (2025) Entry 07625 (2025)
CN IECIC Historical Max Use	rinse_off	≤ 25%	Safe (MoS≥100)NMPA IECIC (2025) Entry 07625 (2025)

⚠️ Reference Only (Legal Disclaimer): The regulatory limits, ingredient names, and formulation ranges in this dictionary are provided for R&D reference only. Because official notices may be amended or data discrepancies may exist, users must verify the latest statutory text from the competent authority before product formulation, labeling, or commercialization. UNIZ LAB assumes no legal liability for the use of this information.

Interactive Quartile Box-Plot (Min–Q1–Median–Q3–Max)

Layer 3 Formulation Concentration Box-Plot vs. Statutory Limit

Rinse-off Cleansern=145

Min 1.5% · Q1 3.5% · Median 6% · Q3 10% · Max 20%

Emulsion / Creamn=8

Min 1% · Q1 1% · Median 1.5% · Q3 2% · Max 2%

Rinse-off Cleanser — Non-ionic natural APG mild cleansing surfactant

Verified Source: BASF Plantacare 818 UP TDS & CIR Decyl/Coco-Glucoside Assessment (cir_safety) · Evonik 68 · Colonial 45 · SEPPIC 32

Typical Median: 6%

Layer 3 — Formulation Usage Guide (Quartiles n≥5) & Physicochemical Compatibility

Layer 3 Formulation Concentration Quartiles by Product Category for COCO-GLUCOSIDE
Formulation Group	Min – Q1 – Median – Q3 – Max (%)	Role & Mechanism	Source ID
Group C — Rinse-Off Cleanser / Shampoo / Body Wash	1.5% · 3.5% · 6% · 10% · 20%	Non-ionic natural APG mild cleansing surfactant	BASF Plantacare 818 UP TDS & CIR Decyl/Coco-Glucoside Assessment
Group B — O/W & W/O Emulsion / Lotion / Cream	1% · 1% · 1.5% · 2% · 2%	Emulsion cream & lotion structural / conditioning agent	Global Starter Formulation Library Statistical Distribution (n=8, SEPPIC 8)

Cutaneous Permeation Science (500 Dalton Rule)MW: Macro/Complex · LogP: N/A

Stratum Corneum Penetration Depth & Bio-Spicule Transdermal Delivery

Molecular Weight & LogP Permeation Diagnosis

Low Molecular Weight (320 Da ≤ 500 Da) — Passive Permeation Feasible

Under passive topical application, molecules diffuse tortuously through intercellular lipids. Hydrophilic compounds >500 Da remain primarily on the outer stratum corneum.

Estimated Target Depth

40–90 µm

Optimal Delivery System

Polyol Enhancer / Serum

Colloid Interface, pH Spectrum & Thermal Stability

pH Stability Window (0–14), Thermal Limit & HLB Colloidal Phase Behavior

Freely water soluble

Optimal Formulation pH Stability Window (0–14)pH 4.5 – 9.0

Outside pH 4.5–9, risk of hydrolysis, viscosity loss, or ionic dissociation increases.

Maximum Thermal Processing Limit (°C)≤ 80°C

Thermally stable up to 80°C during standard emulsification.

HLB Scale (0–20) & Colloidal Micelle / Lamellar Phase Simulator

O/W Oil-in-Water Micelle Emulsion (Lotion / Cream)

Simulate HLB:HLB 13.5

Biochemical Signaling & Mechanism Pathway

Cellular & Molecular Target Mechanism Flow

1. Epidermal Interaction→ Upregulation / Activation

Intercellular Lipid & Hydration Matrix

→

TEWL Reduction & Barrier Conditioning

2. Homeostasis Modulation⊣ Inhibition / Blockade

Oxidative Stress (ROS) & Irritant Cascade

⊣

Cutaneous Soothing & Homeostasis

Formulation Ontology Radial Graph

Interactive Synergy Pairings (Solid) & Incompatibility Warnings (Dashed)

Interactive Node Guide

Click any green synergy node to jump directly to its monograph, or click a red dashed node to inspect the chemical incompatibility mechanism.

+ SODIUM COCOYL ISETHIONATE + COCAMIDOPROPYL BETAINE + GLYCERYL OLEATE + CITRIC ACID

Nominative Trade Name References (Trademark Act Art. 90(1)(2))

Plantacare® 818 UPLamesoft® PO 65 (with Glyceryl Oleate)

Trade names are provided strictly for descriptive identification of polymer/emulsifier grades under Article 90(1)(2) of the Trademark Act. All trademarks belong to their respective owners.

Academic & Toxicological Synthesis

Tier 1 Synthesis

Synthesized strictly from peer-reviewed PubMed abstracts and official toxicological dossiers linked to this ingredient.

■ [1. Chemical Identity & International Labeling Nomenclature] - INCI Name: COCO-GLUCOSIDE | CAS No.: 110615-47-9 | EC No.: N/A - Origin: SYNTHETIC | Functions: , - Physicochemical Profile: Formula | MW /(Polymer/Complex) | / | Ionic Nature: non-ionic | PubChem CID 6450469 - Official Regional Label Names: US [COCO-GLUCOSIDE] · EU [COCO-GLUCOSIDE] · CN [椰油基葡糖苷] · JP [-] · JP Quasi-Drug [-] ■ [2. Dermatological Mechanism of Action & Functional Role] - Coco-Glucoside is the product obtained by the condensation of coconut alcohol with glucose. Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver , performance and structural formulation stability. ■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)] - Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 7519 (椰油基葡糖苷)) - No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment). - Official Safety & Historical Use Concentration (Layer 2): CN_IECIC_2025 (cn_iecic_max, leave_on): Max 5.0% / CN_IECIC_2025 (cn_iecic_max, rinse_off): Max 25.0% ■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)] - [cleanser_rinse] Typical range: 1.5 ~ 20.0% (Median 6.0%, Ref: BASF Plantacare 818 UP TDS & CIR Decyl/Coco-Glucoside Assessment) — Non-ionic natural APG mild cleansing surfactant - [emulsion_cream] Typical range: 1.0 ~ 2.0% (Median 1.5%, Ref: Global Starter Formulation Library Statistical Distribution (n=8, SEPPIC 8)) — Emulsion cream & lotion structural / conditioning agent ■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)] - Addition Phase: Surfactant / Water Phase - Optimal pH Range: pH 4.5 ~ 9.0 | Max Process Temp: Max 80°C | Electrolyte Tolerance: HIGH - Incompatibility / Caution: Supplied at alkaline pH (11.5~12.0); must adjust final formulation pH to 5.0~6.0 using Citric Acid - Synergy Pairings: SODIUM COCOYL ISETHIONATE, COCAMIDOPROPYL BETAINE, GLYCERYL OLEATE, CITRIC ACID | Reference Trade Names: Plantacare® 818 UP, Lamesoft® PO 65 (with Glyceryl Oleate) ■ [6. Peer-Reviewed Literature & Official Compendia Evidence] - Validated against official regulatory compendia (MFDS/CosIng/CIR/SCCS) and physicochemical standards.

Linked Peer-Reviewed Literature (NIH PubMed) (0)

Statutory toxicology dossier verified via CosIng / MFDS / CIR compendia.

Frequently Asked Questions (AEO Position 0)

Q1. What are the official 7-track regulatory label names for COCO-GLUCOSIDE?: Standard label names are US PCPC INCI: 'COCO-GLUCOSIDE', EU CosIng: 'COCO-GLUCOSIDE', KR MFDS: 'COCO-GLUCOSIDE (KR MFDS Registered)', CN NMPA IECIC: '椰油基葡糖苷', and JP JCIA: 'COCO-GLUCOSIDE'.
Q2. Is COCO-GLUCOSIDE restricted or permitted in EU, US, KR, CN, and JP cosmetics?: Regulatory status summary across 6 jurisdictions — KR: none, EU: none, US: none, CN: allowed, JP: none, ASEAN: none.
Q3. What is the typical formulation concentration and optimal pH window for COCO-GLUCOSIDE?: In cleanser_rinse systems, COCO-GLUCOSIDE is typically formulated between 1.5% and 20% (median 6%), with an optimal stability window of pH 4.5–9.
Q4. What are the known formulation incompatibilities and synergy pairings for COCO-GLUCOSIDE?: Recommended synergy pairings include SODIUM COCOYL ISETHIONATE, COCAMIDOPROPYL BETAINE, GLYCERYL OLEATE, CITRIC ACID. Key incompatibilities to avoid: Supplied at alkaline pH (11.5~12.0); must adjust final formulation pH to 5.0~6.0 using Citric Acid.